The university is located in two major campuses, namely Sihhiye and Beytepe Campuses. Sihhiye (Central) Campus was built in the Hacettepe neighborhood of Ankara. Its surface area is 209.071 m² of which 352.181 m² is constructed area. There are three faculties (i.e. Dentistry, Pharmacy and Medicine), six institutes (i.e. Child Health, Public Health, Neurological Sciences and Psychiatry, Population Studies, Oncology, and Health Sciences), and five schools (i.e. Home Economics, Physical Therapy and Rehabilitation, Nursing, Health Services, and Health Technology). The Department of Health Administration of the Faculty of Economics and Administrative Sciences is also in the Sihhiye Campus. Furthermore, there are the 1150 bed Adult Hospital, the 350 bed Ihsan Dogramaci Children's Hospital and the Oncology Hospital. Other facilities in this campus are 2176 bed student dormitories and the 841 bed student guesthouses, a library, a covered gym, cafeterias, and open/covered parking lots.

Beytepe Campus, the other major settlement of the University, is located on the Beytepe district in direction of Ankara-Eskisehir highway, 20 kilometers away from the Central Campus. The surface area covers 5.877.528 m² of which 190.325 m² is constructed area. There are 6 faculties (i.e. Letters, Education, Science, Fine Arts, Economics & Administrative Sciences and Engineering), 7 institutes (i.e. Ataturk Institute for Modern Turkish History, Informatics, Science and Engineering, Social Sciences, Nuclear Sciences, Fine Arts, Turkology Studies) and 4 Schools (i.e. School of Vocational Technology, The Hacettepe Vocational School, Foreign Languages, Sport Sciences & Technology). Other facilities in the Beytepe Campus are a 2.478 bed student dormitory, a 600 bed student guesthouse, 90 pupil kindergarten (0-6 years) and a 1022-pupil-primary school, a library, several cafeterias, a covered gym and open sports facilities.

Other than these two campuses, there are following five more locations contain a number of units of the university: The Ankara State Conservatory established in 1936 by Ataturk, the founder of Turkish Republic has already been functioning in the Besevler Campus located at the Bahcelievler neighborhood of Ankara since 1982 that it was attached to the Hacettepe University. There are 20 blocks of teaching and performance buildings and 360 bed student dormitory which have 30.064 m² of constructed and covered area in the campus which was built on a surface area of 24.850 m².

The Department of Social Services of the Faculty of Economics and Administrative in the Kecioren Campus located at the Kecioren neighborhood of Ankara has 5 blocks of buildings having constructed and covered area of 7.484 m² in a surface area of 11.175 m². 5.100 m² of the Opera Campus in the Altındağ district of Ankara, a real property accessed to Gazi University by treasury was transferred to the Hacettepe University in July 19, 1997. Vocational School of Social Sciences is serving in this campus.

There are the Polatli Technical Sciences and the Health Services Vocational Schools which were established in 1998 and started educational activities in the academic year 1998-1999 in the Polatli Campus located in Polatli district of Ankara.

Bala Vocational School which was established in 2005, and started educational activities in the academic year 2005-2006 is located in the Bala Campus.